ارتباط با ما
با ما تماس بگیرید
0086-21-58386256
0086-21-58386256
The stimulating effect of germanium on oxidizing enzymes such as aldehyde reductase [34], has also been established. Hence, germanium-containing drugs have long ... ple, for the best-known organic germanium sesquioxide Ge-132 oral toxicity for mice is LD 50 > 6300 mg/kg, oral for rats is >10000 mg/kg and intravenous toxicity for …Web
The organic germanium compounds (Ge-132, 373, 385), derivatives of amino acids containing germanium as the linker of framework, were combined by the box titration method to determine the dose that ...Web
The antioxidant activity of Ge-132 (2-carboxyethylgermanium sesquioxide, [(O 0.5) 3 GeCH 2 CH 2 COOH] n), a widely used organic germanium dietary supplement, was assessed by cyclic voltammetry and through its interaction with a stable radical 2,2,-diphenyl-1-picrylhydrazyl (DPPH) monitored by UV-Vis and EPR spectroscopy in water, …Web
Organic germanium compounds have been reported to inhibit the detoxification enzyme glutathione-S-transferase. Germanium compounds are readily absorbed following oral exposure. Germanium is distributed throughout the body tissues, with some enrichment in the kidney and thyroid. Organic germanium is thought not to …Web
Poly-trans-[(2-carboxyethyl) germasesquioxane], Ge-132 is a water-soluble organic germanium compound. Oral intake of dietary Ge-132 changes fecal color and we attempted to identify the fecal red pigment, which increased by the intake of dietary Ge-132. Sprague Dawley rats were given diets containing Ge-132 from 0 to 0.5% concentration.Web
The stimulating effect of germanium on oxidizing enzymes such as aldehyde reductase [ 34] has also been established. Hence, germanium-containing …Web
Patent application by organic germanium production method. 1987: Patent acquisition in the manufacture of organic germanium. 1988 "Spirulina" research started. 1994: ... Kumejima Enzyme Plant 37, Ou, Shimajirigun Kumejimacho, Okinawa 901-3106, Japan ℡ 098-896-7233: Company Profile; Message from the President; Company Overview;Web
Germanium (Ge) is a rare heavy metal and is known to toxic to plants at high level. However, there is little evidence about the Ge effect on plant growth. Here, we investigated the effect of inorganic (GeO2) and organic (Ge-132) germanium on lettuce growth by treatment with various concentrations of GeO2 and Ge-132. Under GeO2 …Web
1. Introduction. Inorganic germanium is used in semiconductors and various optical applications [].The organogermanium compound poly-trans-[(2-carboxyethyl) germasesquioxane] (Ge-132; repagermanium) was first synthesized by Oikawa et al. in 1967, and its structure was reported in 1976 [2,3].A hydrolysate of Ge-132,3 …Web
The structures of Ge-132 and trihydroxy germyl propanoic acid, a product of the hydrolysis of Ge-132, are shown in Figure 1. Ge-132 has many therapeutic effects including anticarcinogenic and antihypertensive effects, the alleviation of rheumatism, …Web
We used Bio-Germanium, an organic germanium compound naturally synthesized via a yeast fermentation process. An 8-week randomized, double-blind, …Web
Poly-trans- [ (2-carboxyethyl) germasesquioxane] (Ge-132) is the most common organic germanium compound. This compound has many physiological effects, which are mediated via the modulation of ...Web
The Oral Intake of Organic Germanium, Ge-132, Elevates α-Tocopherol Levels in the Plas-ma and Modulates Hepatic Gene Expression Profiles to Promote Immune Activation in Mice May 2015Web
Introduction. Germanium is a naturally occurring ultratrace element with a wide application range, from the electronics industry to the dietary supplement industry [1, 2].Organic germanium has been reported to be a therapeutic agent with anticancer [], antitumor [4, 5], antiaging [6, 7], antiviral [] and anti-inflammatory [9, 10] effects; its …Web
Cytochrome P-450 enzyme catalyzes many drugs and endogenous compounds by oxidation or reduction, and reduces the toxicity (phase I reaction) ... We evaluated the function of a water-soluble organic germanium compound, Ge-132, in the induction of a red pigment, which was identified as PpIX. Ge-132 affected the regulation …Web
Germanium and human health. Germanium is naturally present in water and food, as it exists in soil, rocks, animals, and plants in organic and inorganic forms (Kang et al. 2001).Moreover, it is used in industry as a semiconductor and in the manufacture of phase-change optical magnetic discs, such as DVD-RAM and DVD-RW (Lin et al. …Web
In 1967, Dr. Asai Kazuhiko succeeded in synthesizing before the rest of the world water-soluble organic germanium, called "Asaigermanium". Asai Germanium Research Institute has been challenging new research and its application for more than half a century (55 years). ... Cancer-enzyme 9000 - to buy from Prof. Dr. Frank Lampe from 187,90 EUR ...Web
Poly-trans-[(2-carboxyethyl) germasesquioxane] (Ge-132) is the most common organic germanium compound. The ingestion of Ge-132 promotes bile secretion.Web
Organic germanium is known to possess various biological and pharmacological activities, and is often used in medicine for purposes such as anti-tumor, antiviral, ... Germanium is absorbed by hydrochloric acid or enzymes and then transported to tissues and organs through the bloodstream in order to carry out its biological function .Web
nogermanium by chemical reactions of germanium with semiconductor proper-ty with organic compounds [1]. This is a soluble compound and was named poly-trans-2-carboxyethyl-germasesquioxane (Ge-132) in those days [1]. At pre- sent, this compound, which is generally called organogermanium (Ge-132), namelyWeb
The antioxidant activity of Ge-132 (2-carboxyethylgermanium sesquioxide, [(O 0.5) 3 GeCH 2 CH 2 COOH] n), a widely used organic germanium dietary supplement, …Web
absorbed by hydrochloric acid or enzymes and then transported to tissues and organs through the blood-stream in order to carry out its biological function [23]. ... Oral administration of organic germanium Ge-132 can increase the level of α-tocopherol in the plasma and reg-ulate liver gene expression proles, promoting immune activation in mice ...Web
Therefore, organic germanium is a kind of "internal Chizhevsky chandelier" [10, 11]. At the same time, organic germanium compounds are nontoxic, they have no side reactions and function in the body for a long time, and hence can be regarded as extremely prom-ising for use in medicine [5, 6]. Dolaychuk et al. [13] reported the results of ...Web
Germanium is distributed dispersedly in the earth's crust, where only a few independent deposits of the element exist; the average abundance of germanium is 1.5 × 10 −4 % (Arroyo and Fernandez-Pereira, 2008).Natural germanium resources include germanium-bearing zinc ores, coal (e.g., lignite), and other germanium-containing …Web
Kumejima Enzyme Drink is sterilized by heating at about 90-92 °C for 1 to 2 minutes according to the Food Sanitation Law, but some of them are heat-resistant enzymes which do not die even at 100 °C or higher. Approximately 8.8 million yeasts can be confirmed per 1 ml in Kumejima Enzyme Drink after heating and filling. Yeast in Kumejima Enzyme ...Web
Glutathione and glutathione-dependent enzymes of the rat liver after different doses of Sanumgerman ... proxi-germanium and so on (Han et al., 2007; Cheong et al., 2009). Organic germanium compounds, especially for Ge-132, has been widely used as medical applications and dietary supplement since its therapeutic attributes, which …Web
Japan Algae Co., Ltd. super food with amazing. nutritional value. domestic production. (manufactured in-house) purity. blue color extracted. from spirulina. Enzyme power of Okinawa.Web
Designing highly active nanozymes for bioanalysis and environmental sensing remains a challenge. In this study, transition metal, palladium (Pd) and iron (Fe), doped germanium oxide (GeO 2) nanozyme was designed and optimizedpared with the pristine GeO 2 nanozyme, the transition metal doped GeO 2 nanozyme have lower …Web
